https://ogma.newcastle.edu.au/vital/access/ /manager/Index en-au 5 https://ogma.newcastle.edu.au/vital/access/ /manager/Repository/uon:9680 Sat 24 Mar 2018 08:39:14 AEDT ]]> https://ogma.newcastle.edu.au/vital/access/ /manager/Repository/uon:29169 p = 0.480) and uncontrolled asthma at =2 study visits (21.3-11.3%; p = 0.078). Conclusions: These findings demonstrate the potential impact of an AMS in improving asthma control during pregnancy, supporting the need for an adequately powered RCT to determine its clinical- and cost-effectiveness.]]> Sat 24 Mar 2018 07:35:45 AEDT ]]> https://ogma.newcastle.edu.au/vital/access/ /manager/Repository/uon:29323 4500 g). Results: On average, women with a normal BMI gained 1 kg/m² between first and second pregnancies, while women who were overweight or obese gained 1.37 kg/m². Among women with a normal BMI in their first pregnancy, a BMI increase of ≥4 kg/m² was associated with increased risk of developing GDM (aRR 1.97; 95% CI 1.22–3.19), a macrosomic (aRR 4.06; 95% CI 2.25–7.34) or LGA infant (aRR 1.31 0.96–1.78) in the second pregnancy, while a reduction in BMI (≤–2 kg/m²) was associated with an increased risk of SGA (aRR 1.94; 1.19–3.16). Among women who were overweight or obese in their first pregnancy, a BMI increase of ≥2–4 and ≥4 kg/m² was associated with increased risks of developing GDM in the second pregnancy (aRR 1.39; 95% CI 1.01–1.91 and aRR 1.64 95% CI 1.16–2.31; _Ptrend< 0.001), while no associations were observed for a BMI increase and risk of a macrosomic, SGA, or LGA infant. In contrast, reduction in BMI (≤–2 kg/m²) was associated with a reduced risk of GDM (aRR 0.58 95% CI 0.37–0.90) and SGA (aRR 0.47; 95% CI 0.25–0.87). Conclusion: Increases in BMI between pregnancies is associated with an increased risk for perinatal complications, even in normal-weight women, while a reduction in BMI is associated with improved perinatal outcomes among women who are overweight/obese. Inter-pregnancy weight control is an important target to reduce the risk of an adverse perinatal outcome in a subsequent pregnancy.]]> Sat 24 Mar 2018 07:34:20 AEDT ]]>